Esposizione occupazionale e malattie mentali

Roma, 21 ottobre 2004.
Alleghiamo l'Abstract di un art. pubblicato sul numero di Novembre di
Epidemiology (rif.: www.epidem.com).
Lo studio dimostra che l'esposizione occupazionale a campi elettromagnetici a
frequenza estremamente bassa, con intensitÓ del campo magnetico uguale o
maggiore di 0.2 microTesla, determina un maggio rischio di malattia di
Alzheimer e demenza.
La ricerca Ŕ stata condotta a Stoccolma, in una comunitÓ priva di malattie
mentali e costituita da 931 persone di etÓ maggiore o uguale a 75 anni per
rilevare i casi di tali malattie.
La comunitÓ Ŕ stata seguita dal 1987-1989 fino al 1994-1996. La demenza Ŕ
stata diagnosticata in 265 soggetti, dei quali 202 affetti dalla malattia di
Alzheimer.
Fra gli uomini Ŕ stato riscontrato un maggior rischio pari a 2.3 - 2.4 volte
per l'Alzheimer e a 2 - 2.5 volte per la demenza. Non Ŕ stata riscontrata
associazione fra le donne.
Cari saluti.
Raffaele Capone
Coordinamento dei Comitati di Roma Nord.
Da: "cittadiniattivi\@libero\.it"

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Occupational Exposure to Electromagnetic Fields and Risk of Alzheimer's
Disease.

Epidemiology. 15(6):687-694, November 2004.
Qiu, Chengxuan *; Fratiglioni, Laura *; Karp, Anita *; Winblad, Bengt *;
Bellander, Tom +
Abstract:
Background: Extremely-low-frequency magnetic field (ELF-MF) exposure is
suspected to increase the risk of Alzheimer's disease. Such fields are present
in the vicinity of electrical motors and other electric appliances containing
coils.
Methods: We investigated lifetime occupational ELF-MF exposure in relation to
Alzheimer's disease and dementia among a community dementia-free cohort (n =
931) age 75 years and older in Stockholm, Sweden. This cohort was followed
from 1987-1989 until 1994-1996 to detect dementia cases (Diagnostic and
Statistical Manual of Mental Disorders, revised 3rd edition criteria).
Information on lifetime job history was obtained by interview, usually of next
of kin. ELF-MF exposure was assessed using a job-exposure matrix, measurement
on historical equipment, and expert estimation. We analyzed the data with Cox
models controlling for potential confounders.
Results: Dementia was diagnosed in 265 subjects, including 202 with
Alzheimer's disease. Among men, ELF-MF exposure >=0.2 [mu]T in lifetime
principal job was related to multivariate-adjusted relative risks of 2.3 (95%
CI = 1.0-5.1) for Alzheimer's disease and 2.0 (1.1-3.7) for dementia. We found
no association among women. A similar sex-specific pattern was seen for the
associations with average ELF-MF exposure throughout the work life. A
dose-response relation was suggested in men, with multivariate-adjusted
relative risks of 2.4 (0.8-6.8) for Alzheimer's disease and 2.5 (1.1-5.6) for
dementia for the upper tertile of lifetime average exposure.
Conclusions: Long-term occupational exposure to a higher ELF-MF level may
increase the risk of Alzheimer's disease and dementia in men. Similar patterns
were not seen in women, which may in part be the result of a greater exposure
misclassification in women than in men.
(C) 2004 Lippincott Williams & Wilkins, Inc.